Our group works on computational fluid dynamics (CFD), computational biophysics, high-performance computing, and reproducibility. In one project now we have coupled a boundary element method solver for protein electrostatics with our fast multipole method software, and show we can compute the electrostatic potential and solvation energy of a full virus. We have worked for many years with the fast multipole method, developing open source software for this interesting and powerful algorithm. In CFD, we have been working with the immersed boundary method to study the aerodynamics of gliding and flying animals. We have a strong commitment to reproducible research and have worked over the years to improve our practices and share our experiences. (I am an expert in reproducibility and was called to serve the National Academies in a study committee on the topic.) The group writes research software following an open development model, and we are strong advocates of open source software and open science.